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Toxicology and Industrial Health, Vol. 22, No. 6, 249-254 (2006)
DOI: 10.1191/0748233706th266oa

Health hazards by lead exposure: evaluation using ASV and XRF

D'souza Sunil Herman

Department of Biochemistry and Biophysics, St. John's Medical College, Koramangala, Bangalore-560034, Karnataka, India, hermansdsouza{at}rediffmail.com

Menezes Geraldine

Department of Biochemistry and Biophysics, St. John's Medical College, Koramangala, Bangalore-560034, Karnataka, India

Clark C Scott

Department of Environmental Health, 222 Kettering Laboratory, University of Cincinnati Medical Centre, Cincinnati, OH 45267-0056, USA

Thuppil Venkatesh

Department of Biochemistry and Biophysics, St. John's Medical College, Koramangala, Bangalore-560034, Karnataka, India

Globally, of many toxic heavy metals, lead is the most widely used for various purposes, resulting in a variety of health hazards due to environmental contamination. Lead in the workplace enters the workers through inhalation of lead-contaminated air, by ingestion, and sometimes through dermal exposure. Furthermore, exposure outside the workplace can occur from inhalation of lead-contaminated air, ingestion of lead-contaminated dust and soil, consumption of lead polluted water, lead adulterated food and lead supplemented medicine. In the present study, an evaluation of blood lead was carried out with the aid of a 3010 B lead analyser, based on the principle of anodic stripping voltametry (ASV), and environmental lead in paint, soil and dust samples by a field portable X-ray fluorescence (XRF) analyser. This revealed a high incidence of lead toxicity in most of the lead-based industrial workers in the four facilities tested in India and high levels of lead in the environmental samples. Developed countries have complied with the global standards for regulating environmental lead poisoning in the workplace, eliminating to some degree excessive exposure to lead. A developing country, such as India, can tackle this problem by implementing national and international policies. The US Occupational Safety and Health Administration (OSHA) and Environmental Protection Agency (EPA) regulations, which are of prime importance, or similar regulations, can be adapted for use in India and implemented to minimize lead exposure and to reduce the resultant health hazards.

Key Words: blood lead levels • DPASV • health hazards • XRF


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