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ATSDR evaluation of health effects of tungsten and relevance to public health

Agency for Toxic Substances and Disease Registry (ATSDR), U.S. Department of Health and Human Services, Atlanta, GA, USA

Daphne B. Moffett

Agency for Toxic Substances and Disease Registry (ATSDR), U.S. Department of Health and Human Services, Atlanta, GA, USA

Zemoria A. Rosemond

Agency for Toxic Substances and Disease Registry (ATSDR), U.S. Department of Health and Human Services, Atlanta, GA, USA

David W. Wohlers

Syracuse Research Corporation, North Syracuse, NY, USA

The Agency for Toxic Substances and Disease Registry prepares toxicological profiles, as part of its mandate, on hazardous chemicals found at Comprehensive Environmental Response, Compensation, and Liability Act National Priorities List sites that have the greatest public health impact. These profiles comprehensively summarize toxicological and environmental information. This article constitutes the release of portions of the Toxicological Profile for tungsten. The primary purpose of this article is to provide public health officials, physicians, toxicologists and other interested individuals and groups with an overall perspective on the toxicology of tungsten. It contains descriptions and evaluations of toxicological studies and epidemiological investigations and provides conclusions, where possible, on the relevance of toxicity and toxicokinetic data to public health. Toxicology and Industrial Health 2007; 23: 347—387

Key Words: tungsten • hard metal • developmental • reproductive • neurological • tumor • cancer pulmonary fibrosis • carbide • guidance value • mechanisms • toxicokinetics

Toxicology and Industrial Health, Vol. 23, No. 5-6, 347-387 (2007)
DOI: 10.1177/0748233707076767


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