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Successful treatment of extreme acute lead intoxication

Department of Pediatrics, Jessenius School of Medicine, Comenius University in Bratislava, University hospital in Martin, Martin, Slovak Republic

P Banovcin

Department of Pediatrics, Jessenius School of Medicine, Comenius University in Bratislava, University hospital in Martin, Martin, Slovak Republic

M Jesenak

Department of Pediatrics, Jessenius School of Medicine, Comenius University in Bratislava, University hospital in Martin, Martin, Slovak Republic

J Hamzikova

Department of Pediatrics, Jessenius School of Medicine, Comenius University in Bratislava, University hospital in Martin, Martin, Slovak Republic

D Statelova

Department of Stomatology and Maxilofacial Surgery, Comenius University in Bratislava, University hospital in Martin, Martin, Slovak Republic

Severe acute lead intoxications are rare and are associated with accidental or purposeful ingestion. There were only few cases of severe to fatal poisonings reported in literature in children. We report a case of acute lead intoxication in a child with extremely high lead blood level of 20.4 µmol/L (422.7 µg/dL), who was treated with chelation and in whom significant organ dysfunction did not develop. Documented significant high level above 3.37 µmol/L (corresponding to 70 µg/dL) in this patient persisted for approximately 24 h. Adequate, single or combined chelatation therapy in early phase of acute lead poisoning is essential for the further patient’s outcome.

Key Words: chelation • children • lead poisoning • severe intoxication • successful treatment

Toxicology and Industrial Health, Vol. 25, No. 2, 137-140 (2009)
DOI: 10.1177/0748233709104759


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