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Extra virgin olive oil phenolics: absorption, metabolism, and biological activities in the GI tractDipartimento di Biologia Sperimentale, Sez. Patologia Sperimentale, Università degli Studi di Cagliari, 09042 Monserrato, Italy gcorona{at}unica.it
Molecular Nutrition Group, School of Chemistry, Food and Pharmacy, University of Reading, Reading RG2 6AP, UK
Dipartimento di Biologia Sperimentale, Sez. Patologia Sperimentale, Università degli Studi di Cagliari, 09042 Monserrato, Italy Olive oil, a typical ingredient of the Mediterranean diet, possesses many beneficial health effects. The biological activities ascribed to olive oil consumption are associated in part to its phenolics constituents, and mainly linked to the direct or indirect antioxidant activity of olive oil phenolics and their metabolites, which are exerted more efficiently in the gastrointestinal (GI) tract, where dietary phenolics are more concentrated when compared to other organs. In this regard, we present a brief overview of the metabolism, biological activities, and anticancer properties of olive oil phenolics in the GI tract.
Key Words: colon cancer • GI tract • metabolism • olive oil • polyphenols
Toxicology and Industrial Health, Vol. 25, No. 4-5,
285-293 (2009) |
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