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Toxicology and Industrial Health
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In Vitro Screens From Cns, Liver and Kidney for Systemic Toxicity

Charles A. Tyson

SRI International Menlo Park, California

Neill H. Stacey

National Institute of Occupational Health and Safety The University of Sydney Sydney, Australia

The development and evaluation of in vitro systems from target organs for preliminary assessments of the potential for systemic toxic effects has been receiving increased attention. This review presents a synopsis of progress made in developing toxicity screens for three common target organs and identifies further work needed for more complete validation.

Key Words: central nervous system • hepatocyte • kidney tubule.

Toxicology and Industrial Health, Vol. 5, No. 1, 107-132 (1989)
DOI: 10.1177/074823378900500109
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