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Toxicology and Industrial Health
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Reanalysis of Epidemiological Data for Selenium Anti-Cancer Activity

John H. Lange

Center for Environmental and Occupational Training, Inc. 814 East Pittsburgh Plaza East Pittsburgh, Pennsylvania 15112

Investigations of the health effects of selenium have repeatedly noted an inverse relationship of selenium (both soil and human sera) and decreased prevalence of cancer. This has been found in cross sectional, case-control and ecological study designs. Reanalysis of age-adjusted death rates by cancer site revealed a significant inverse relationship for lung and all cancer with blood selenium. Methodological problems in this type of re search is discussed.

Key Words: 1. Key words: latency period • anti-cancer agent • cancer prevention • ecological analysis

Toxicology and Industrial Health, Vol. 7, No. 4, 319-325 (1991)
DOI: 10.1177/074823379100700407


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